As you know in the all countries of the world some of the websites are blocked by their government or other policies. For example in Pakistan Youtube is blocked for some reasons and all other dirty websites are also blocked in Pakistan that has dirty contents and peoples used different software that unblock these sites with proxy. When they activate proxy server that bypass all the policies that you have applied therefore here is a trick from which you can block hotspot ports and special ips that hotspot shield used.
/ip firewall address-list
add address=157.56.106.0/24 disabled=no list=hotspotshield_zaib
add address=157.56.144.0/24 disabled=no list=hotspotshield_zaib
add address=198.144.116.0/24 disabled=no list=hotspotshield_zaib
add address=204.14.77.0/24 disabled=no list=hotspotshield_zaib
add address=204.14.0.0/16 disabled=no list=hotspotshield_zaib
add address=205.164.34.0/24 disabled=no list=hotspotshield_zaib
add address=209.73.0.0/16 disabled=no list=hotspotshield_zaib
add address=212.118.232.0/24 disabled=no list=hotspotshield_zaib
add address=216.172.138.0/24 disabled=no list=hotspotshield_zaib
add address=216.172.0.0/16 disabled=no list=hotspotshield_zaib
add address=46.0.0.0/8 disabled=no list=hotspotshield_zaib
add address=66.171.229.0/24 disabled=no list=hotspotshield_zaib
add address=68.68.107.0/24 disabled=no list=hotspotshield_zaib
add address=68.68.108.0/24 disabled=no list=hotspotshield_zaib
add address=69.22.168.0/24 disabled=no list=hotspotshield_zaib
add address=69.22.170.0/24 disabled=no list=hotspotshield_zaib
add address=74.115.0.0/16 disabled=no list=hotspotshield_zaib
add address=94.245.121.0/24 disabled=no list=hotspotshield_zaib
add address=69.22.185.0/24 disabled=no list=hotspotshield_zaib
add address=174.129.0.0/16 disabled=no list=hotspotshield_zaib
add address=216.172.135.0/24 disabled=no list=hotspotshield_zaib
add address=67.220.0.0/16 disabled=no list=hotspotshield_zaib
add address=50.0.0.0/8 disabled=no list=hotspotshield_zaib
add address=79.125.0.0/16 disabled=no list=hotspotshield_zaib
add address=75.101.0.0/16 disabled=no list=hotspotshield_zaib
add address=176.56.0.0/16 disabled=no list=hotspotshield_zaib
add address=54.75.0.0/16 disabled=no list=hotspotshield_zaib
add address=54.161.0.0/16 disabled=no list=hotspotshield_zaib
add address=199.188.0.0/16 disabled=no list=hotspotshield_zaib
# Now create Rules to block above address list and additional ports
/ip firewall filter
add action=drop chain=forward comment="Block_Hotspot_Shield_Addresses_(test phase_zaib)" disabled=no src-address-list=hotspotshield_zaib
add action=drop chain=forward comment="Block_Hotspot_Shield_Ports_(test phase_zaib)" disabled=no dst-port=990,179,105,706,5245,3451,15009 protocol=tcp
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